The objective of this study is to identify neural correlates of cognitive improvement after
three months of donepezil HCl in subjects with mild Alzheimer's Disease (AD), measuring the
Functional Hippocampus Connectivity Index (HCI) and Cerebral Blood Flow (CBF) Perfusion in
the Medial Temporal Lobe network. The hypothesis is that donepezil HCl will improve MTL
connectivity and CBF Perfusion in the MTL-projected target regions, which will significantly
correlate with cognitive improvement in mild AD subjects.