Neonatal Brain Ultrasound With CEUS and Elastography

• Status: Not yet recruiting
• Trial end date: 2029-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of our study is to investigate changes of brain perfusion and elasticity in neonates during the time that a neonate is adapting to live outside the womb and during diseases that are suspected to affect neonatal brain perfusion. We use contrast enhanced ultrasound (sulphur hexafluoride) and ultrasound-assisted elastography to evaluate the state of brain perfusion. We will study neonates recruited from the Neonatal Units of Turku University Hospital.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Turku University Hospital

Criteria

Inclusion Criteria:

• Babies less than 7 months treated at the neonatal units of Turku University hospital

Exclusion Criteria:

• Pre-known genetic disease

• Difficult congenital malformations that need surgical treatment

• Central nervous system tumors

• Weight less than 2,5 kg during examination

• Medical history of SonoVue hypersensitivity

• Uncontrolled systemic hypertension

• Systolic pulmonary artery pressure > 90 mmHg

• Unstable cardiovascular state