Overview

Neoantigen-based Personalized DNA Vaccine in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Status:
Recruiting
Trial end date:
2023-07-31
Target enrollment:
Participant gender:
Summary
This is a single institution, open-label, single arm, study assessing the safety, feasibility, and immunogenicity of a personalized neoantigen-based vaccine in subjects with newly diagnosed, unmethylated glioblastoma.
Phase:
Phase 1
Details
Lead Sponsor:
Washington University School of Medicine
Collaborator:
Geneos Therapeutics
Treatments:
Coal Tar
Ipilimumab
Nivolumab
Vaccines