Overview

Neoadjuvant Study of Palbociclib in Combination With Letrozole and Trastuzumab in Stage II-III ER+ HER2+ Breast Cancer

Status:
Terminated
Trial end date:
2020-09-23
Target enrollment:
Participant gender:
Summary
The investigators propose to influence estrogen receptor (ER) signaling by combining endocrine therapy with CDK4/6 inhibition along with trastuzumab in ER+/ human epidermal growth factor receptor 2 (HER2)+ early stage breast cancer.
Phase:
Phase 2
Details
Lead Sponsor:
Washington University School of Medicine
Collaborators:
Pfizer
Rising Tide Foundation
Treatments:
Goserelin
Letrozole
Palbociclib
Trastuzumab