Neoadjuvant Chemotherapy Plus Nephroureterectomy for Locally Advanced Upper Tract Transitional Cell Cancer
Status:
Withdrawn
Trial end date:
2010-04-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test the effectiveness, safety and side effects of two
chemotherapy drugs (gemcitabine and cisplatin) when combined with surgery after chemotherapy
for patients with upper urinary tract cancer. The hypothesis is that undergoing chemotherapy
prior to surgery will have a beneficial effect on prognosis and may improve overall survival
as in patients with bladder cancer, and will allow better tolerance of chemotherapy than if
it were given after surgery.