Overview

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

Status:
RECRUITING
Trial end date:
2030-06-30
Target enrollment:
Participant gender:
Summary
This study is being done to answer the following questions: Is the chance of rectal cancer responding the same if chemotherapy alone is given before limited surgery compared to chemotherapy and radiation therapy given together before limited surgery? If radiation therapy is not given, is quality of life better?
Phase:
PHASE3
Details
Lead Sponsor:
Canadian Cancer Trials Group
Collaborators:
Alliance for Clinical Trials in Oncology
ECOG-ACRIN Cancer Research Group
NRG Oncology
SWOG Cancer Research Network
Treatments:
Capecitabine
Fluorouracil
Leucovorin
Oxaliplatin
Radiation