NatrOVA Photoallergy Study - NatrOVA Creme Rinse in Healthy Volunteers
Status:
Completed
Trial end date:
2008-02-01
Target enrollment:
Participant gender:
Summary
Photoallergic reactions are assumed to be due to a delayed cell-mediated hypersensitivity
response that requires the presence of ultraviolet irradiation. The predictive procedure is,
therefore, based on modification of the Repeated Insult Patch Test (Kaidbey, 1991). Duplicate
sets of patches of test articles are used with exposure of only one set to UV radiation and
subsequent evaluation of both sets for skin reactions in order to compare irradiated versus
non-irradiated test sites.