Overview

National Adaptive Trial for PTSD Related Insomnia

Status:
Recruiting
Trial end date:
2024-06-25
Target enrollment:
Participant gender:
Summary
Many Veterans with posttraumatic stress disorder (PTSD) have trouble sleeping or have frequent nightmares. So far, no medication has been approved for treatment of insomnia in PTSD. The purpose of this research study is to find out if taking medications called trazodone, eszopiclone, or gabapentin can help decrease symptoms of insomnia in patients with PTSD. PTSD is a form of intense anxiety which sometimes results from severe trauma. Symptoms may include nightmares, flashbacks, troublesome memories, difficulty sleeping, poor concentration, irritability, anger, and emotional withdrawal. Insomnia is a disorder that can make it hard to fall sleep, stay asleep or cause a person to wake up too early and not be able to fall back to sleep.
Phase:
Phase 3
Details
Lead Sponsor:
VA Office of Research and Development
Treatments:
Eszopiclone
Gabapentin
Trazodone