Nasal Ocular Reflexes Contribute to Eye Symptoms

• Status: Completed
• Trial end date: 2006-10-01
• Target enrollment: 0
• Participant gender: All

Summary

Eye symptoms of tearing, redness and itching frequently occur in patients with allergic rhinitis or hayfever. The purpose of this trial is to study whether placing an allergen (a substance that causes allergies) directly in your nose can cause you to have eye symptoms as well as nasal symptoms.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Chicago
• Collaborator: GlaxoSmithKline
• Treatments: Azelastine

Criteria

Inclusion Criteria:

• History of grass and/or ragweed allergic rhinitis.

• Positive skin test to grass and/or ragweed antigen.

• Positive response to screening nasal challenge.

Exclusion Criteria:

• Physical signs or symptoms suggestive of renal, hepatic or cardiovascular disease.

• Pregnant or lactating women.

• Upper respiratory infection within 14 days of study start.