Nasal Inhalation of Isopropyl Alcohol for the Treatment of Nausea in Patients With Cancer

• Status: Not yet recruiting
• Trial end date: 2021-12-30
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this research study is to understand the effect of inhalation approaches in reducing nausea in cancer patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: M.D. Anderson Cancer Center
• Collaborator: National Cancer Institute (NCI)
• Treatments: Ethanol

Criteria

Inclusion Criteria:

• Rate current severity of acute/chronic nausea >= 4 on NRS (Numeric Rating Scale)

• Diagnosis of cancer

• Able to read/write in English

• Referred to supportive care service as an inpatient or outpatient

• Rate anxiety as =< 4 on ESAS-FS (Edmonton Symptom Assessment Scale-Financial Distress and Spiritual Pain)

• Participants must agree to inhale isopropyl alcohol

Exclusion Criteria:

• Received anti-emetics in the last 30 minutes

• Received medical procedures (e.g. blood draws) which required exposure of isopropyl alcohol in the last 30 minutes

• Inability to inhale through nares (including recent upper respiratory infection)

• Known allergy to isopropyl alcohol

• Delirium (i.e., score >= 7 on the Memorial Delirium Assessment Scale [MDAS])

• Have never been on anti-emetics during the course of the treatment here (anti-emetic naive)