Nasal Administration of Sufentanil+Ketamine for Procedure-related Pain in Children

• Status: Completed
• Trial end date: 2013-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study is to investigate the absorption and clinical effect of nasal administration of an analgesic nasal spray containing sufentanil+ketamine for pain related to medical procedures in hospitalized children.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Danish University of Pharmaceutical Sciences
• Collaborator: Rigshospitalet, Denmark
• Treatments: Ketamine; Sufentanil

Criteria

Inclusion Criteria:

• Children and adolescents treated at the University Hospital, Rigshospital

• Painful medical procedure related to the patients treatment

• Patient and/or the parents must be able to understand and speak danish

• Negative pregnancy test for girls, when relevant

• Signed informed consent

• Only a light meals or no meals have been ingested 2 hours prior to inclusion

Exclusion Criteria:

• Allergy to sufentanil or ketamine

• Abnormal nasal cavity

• Have been treated with sufentanil and/or ketamine during the last 48 hours

• Nasal obstruction (rhinitis)