Naltrexone Treatment of Alcohol Abuse in Schizophrenia
Status:
Completed
Trial end date:
2008-05-01
Target enrollment:
Participant gender:
Summary
The primary purpose of this study is to determine whether naltrexone is effective in the
treatment of alcohol dependence and abuse in patients with schizophrenia and schizoaffective
disorder. Hypotheses are as follows:
hypothesis 1: Naltrexone will be more effective than placebo in reducing alcohol use.
hypothesis 2: Patients responding to naltrexone by reducing alcohol use will also show
reductions in severity of psychiatric symptoms and utilization of inpatient and emergency
psychiatric services.
hypothesis 3: Severity of psychiatric symptoms and amount of service utilization will
correlate positively with alcohol use.
Phase:
Phase 4
Details
Lead Sponsor:
State University of New York - Upstate Medical University
Collaborator:
National Institute on Alcohol Abuse and Alcoholism (NIAAA)