Naltrexone Implants vs. MMT Among Inmates in the Norwegian Correctional Services

• Status: Completed
• Trial end date: 2008-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this clinical trial is to study the efficacy and safety of naltrexone implants as a relapse prevention for opiate addicted inmates about to be released from prison. The experimental group is compared with a control group that commences methadone maintenance treatment before release.

The hypothesises are that quality of life and criminal behaviour improve significantly in both groups compared to the month before incarceration. The experimental group is going to have significant less days with opioid use compared to the MMT group.

We hypothesize furthermore that the implants can prevent death related to opiate overdose up to 6 months after commenced treatment.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Oslo
• Collaborator: The Research Council of Norway
• Treatments: Methadone; Naltrexone

Criteria

Inclusion Criteria:

• opiate addiction

• living in greater Oslo area

Exclusion Criteria:

• psychosis / major depression, currently not treated

• pregnancy

• liver enzymes: ASAT or ALAT > threefold above upper boundary