Nalbuphine, Fentanyl and no Additive to Local Anaesthetic Mixture

• Status: Completed
• Trial end date: 2019-05-18
• Target enrollment: 0
• Participant gender: All

Summary

Nalbuphine has been used as an adjuvant to bupivacaine in intrathecal,epidural, caudal anesthesia and peripheral nerve blocks showing an increase in the efficacy and the duration of postoperative analgesia. The aim of this study is evaluation of the effect of 4 mg Nalbuphine when used as an adjuvant to a local anesthetic mixture in peribulbar block undergoing posterior chamber surgery in adult patients and comparing it with adding Fentanyl 20 μg to LAM and LAM alone

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Treatments: Anesthetics; Anesthetics, Local; Bupivacaine; Fentanyl; Nalbuphine

Criteria

Inclusion Criteria:

• patients aged 40-70 years.

• both sex.

• ASA physical status Ι&II.

• Patient with axial globe length below 26

Exclusion Criteria:

• Refusal of the patient to participate in the study.

• Coagulation abnormalities(INR>1.4).

• More than ASA II.

• High myopia with axial length more than 26 mm.

• Mentally retarded patients and failure of proper communication as in deafness .

• Morbidly obese patients(BMI>35)

• Patients with glaucoma (increased IOP>20mmgh)

• Patients with history of hypersensitivity to study drugs