Overview

Nal-iri/lv5-fu Versus Paclitaxel as Second Line Therapy in Patients With Metastatic Oesophageal Squamous Cell Carcinoma

Status:
Recruiting
Trial end date:
2023-04-15
Target enrollment:
Participant gender:
Summary
The aim of our study is to evaluate the efficacy and safety of NALIRI plus 5FU versus paclitaxel as a second-line therapy in patients with locally advanced or metastatic ESCC who had failed to cisplatin- or oxaliplatin-based first-line chemotherapy. The hypotheses are as follows: H0: the percentage of patients alive at 9 months of 40% is not useful. H1: the percentage of patients alive at 9 months of 60% is expected.
Phase:
Phase 2
Details
Lead Sponsor:
Federation Francophone de Cancerologie Digestive
Collaborator:
Shire
Treatments:
Albumin-Bound Paclitaxel
Paclitaxel