Despite the prevalence of cannabis use among the PTSD population and self-reports that it is
used to help cope with PTSD symptoms, the direct effects of cannabis on PTSD symptomology are
unknown. The purpose of this placebo-controlled, within-subject study is to assess the
effects of smoked cannabis and orally administered nabilone, a synthetic analog of THC, the
primary psychoactive component of cannabis on multiple dimensions of PTSD symptomatology in
cannabis smokers with PTSD.