NSAID Use in Postpartum Hypertensive Women

• Status: Terminated
• Trial end date: 2017-10-08
• Target enrollment: 0
• Participant gender: Female

Summary

Women who have the diagnosis of hypertension (pre-pregnancy and pregnancy induced) and deliver an infant via vaginal delivery will be placed into two groups in the postpartum period. One group will receive Ibuprofen for pain control and the other group will be given Tylenol. Blood pressures during the postpartum period will then be collected and compared in order to see if NSAIDs use increases blood pressure.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: St. Louis University
• Treatments: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Ibuprofen

Criteria

Inclusion Criteria:

• vaginal delivery

• diagnosis of chronic hypertension, chronic hypertension with superimposed preeclampsia

• preeclampsia without severe features

• preeclampsia with severe features gestational hypertension without severe range blood pressures

• gestational hypertension with severe range blood pressures

• singleton pregnancies

Exclusion Criteria:

• Cesarean Delivery

• no diagnosis of hypertensive disorder

• chronic or acute renal disease

• allergy to ibuprofen or acetaminophen

• lupus

• multiple order pregnancies (twins, triplets)

• Narcotic addiction/ in treatment for substance abuse/ current prescription drug user/ current use of illegal drugs