NO Donors and Inhibitors to Study Imbalance of Nitrogen Stress and Antioxidant Defense in COPD
Status:
Completed
Trial end date:
2006-07-01
Target enrollment:
Participant gender:
Summary
The primary aim of this study is to investigate the effects of oral and inhaled
administration of L-arginine and of inhaled aminoguanidine on bronchial and alveolar exhaled
NO and NO metabolites in exhaled breath condensate, induced sputum, nasal lavage and mouth
wash fluid in healthy non-smokers, current smokers and patients with COPD.