Overview

NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab

Status:
Not yet recruiting
Trial end date:
2024-12-01
Target enrollment:
Participant gender:
Summary
This is a Phase 1 study with Phase 2 expansion cohort. Phase 1 will assess the safety and tolerability of autologous expanded NK cells in combination with irinotecan, temozolomide, and dinituximab. The phase 2 of the study will estimate the response to treatment.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Nationwide Children's Hospital
Collaborator:
Ohio State University
Treatments:
Antibodies, Monoclonal
Ch14.18 monoclonal antibody
Dinutuximab
Irinotecan
Sargramostim
Temozolomide