The Impact of Ticagrelor on Coronary Atherosclerotic Lipid Pool and Inflammation Assessed by
Near-Infrared Spectroscopy study will evaluate whether ticagrelor leads to a 20% reduction in
the LCBI with NIRS/IVUS suggesting coronary plaque stabilization and reduced inflammation in
patients already on long-term statin therapy undergoing non-urgent PCI. It is hypothesized
that the treatment with ticagrelor following PCI will lead to a significant 20% reduction in
the lipid pool as measured by NIRS/IVUS at follow-up when compared with baseline imaging,
suggesting a reduction in inflammation and stabilization of the lipid core in atherosclerotic
lesions not treated during the index procedure.