Overview

NCT Neuro Master Match - N²M² (NOA-20)

Status:
Recruiting
Trial end date:
2024-09-30
Target enrollment:
Participant gender:
Summary
The objective of N²M² is the improvement of overall survival of patients with glioblastoma with an unmethylated MGMT promoter based on molecular characterization and use of targeted compounds in a modern trial design. The progression-free survival rate at six months (PFS-6) will be used to make decisions.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
University Hospital Heidelberg
Collaborators:
German Cancer Aid
German Cancer Research Center
National Center for Tumor Diseases, Heidelberg
Treatments:
Atezolizumab
Everolimus
Palbociclib
Sirolimus