NAC Effect on Hox Genes Expressions in RIF

• Status: Completed
• Trial end date: 2017-07-01
• Target enrollment: 0
• Participant gender: Female

Summary

Comparison of the group treated with NAC-supplementation and placebo- administered groups showed elevations in HOXA cluster genes (all members) expression level in endometrium of women with RIF.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Royan Institute
• Treatments: Acetylcysteine; N-monoacetylcystine

Criteria

Inclusion Criteria:

1. Age between 20 and 40 years old

2. At least two IVF failure

3. BMI in the normal range

Exclusion Criteria:

1. Irregular menstrual cycle

2. Taking hormonal drugs except thyroid medication

3. Abnormal karyotype or chromosomal disorders

4. Coagulation problems.