Overview

N-of-1 Trials for Blood Pressure Medications in Adults

Status:
Completed
Trial end date:
2017-12-31
Target enrollment:
Participant gender:
Summary
Many patients want to know which blood pressure medication is the best for them. In this study, we will test the feasibility of a new approach to determining the best blood pressure medication for individual patients by performing an N-of-1 trial in which patients will have the opportunity to test a series of 3 blood pressure medications at escalating doses while carefully measuring their blood pressure and side-effects. At the end of each of these N-of-1 trials, we will ask patients to complete a questionnaire in which they rate their level of satisfaction with this approach to learning about which is the best blood pressure medication for them.
Phase:
Early Phase 1
Details
Lead Sponsor:
Columbia University
Treatments:
Amlodipine
Calcium Channel Blockers
Hydrochlorothiazide
Losartan