N-Acetylcysteine in Critically Ill Patients Undergoing Contrast Enhanced Computed Tomography
Status:
Completed
Trial end date:
2005-05-01
Target enrollment:
Participant gender:
Summary
Critically ill patients frequently undergo contrast enhanced computed tomography (CT) to
establish diagnoses and direct management. Contrast agents can disturb kidney function and
result in kidney dysfunction. The investigators investigated the effects of high dose
N-acetylcysteine (NAC) or placebo, in addition to hydration, in preventing kidney dysfunction
following contrast enhanced CT) in critically ill adults in the intensive care units of two
teaching hospitals.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
St. Michael's Hospital, Toronto Unity Health Toronto