Overview

Myo-Inositol- Based Co-treatment in Women With PCOS Undergoing Assisted Reproductive Technology

Status:
Recruiting
Trial end date:
2021-07-01
Target enrollment:
0
Participant gender:
Female
Summary
This is a prospective comparative randomized controlled study investigating the effect of Myo-Inositol-based co-treatment on oocyte quality measures in women with PCOS.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
American University of Beirut Medical Center
Treatments:
Folic Acid
Inositol
Criteria
Inclusion Criteria:

- Age 18-40 years at the time of enrollment.

- Women diagnosed with PCOS according to the Rotterdam criteria indicated by
oligoamenorrhea (six or fewer menstrual cycles during a period of 1 year),
hyperandrogenism (hirsutism, acne, or alopecia) or hyperandrogenemia (elevated levels
of total or free T) and typical features of ovaries on ultrasound scan.

- Planned IVF/ICSI treatment.

- Normal uterine cavity (as assessed by hysteroscopy or HSG).

- Normal hormonal investigation: TSH and PRL.

Exclusion Criteria:

- Azoospermia.

- Other medical conditions causing ovulatory disorders, such as hyperprolactinemia,
hypothyroidism, or adrenal hyperplasia.

- Hypersensitivity to Myo-Inositol or its derivatives.