Mycophenolate Mofetil (MMF) Versus Intravenous CTX Pulses in the Treatment of Adult Severe HSPN

• Status: Completed
• Trial end date: 2006-01-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is performed to compare the efficacy, safety, tolerability and relapse of MMF vs CTX in the treatment of severe HSPN

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Nanjing University School of Medicine
• Treatments: Mycophenolate mofetil; Mycophenolic Acid

Criteria

Inclusion Criteria:

• 16-50 years

• Biopsy proved HSP

• Proteinuria ≥ 3.0 g/24hr

• Scr < 5.0 mg/dl

Exclusion Criteria:

• Cytotoxic drug treatment such as CTX, CsA, MMF for morn than 1 month-3 months prior to enrolled

• Pregnancy

• Active/serious infections

• Previous diagnosed diabetes mellitus type 1 or 2