Overview

Muscle Relaxation for Pediatric Adenotonsillectomy

Status:
COMPLETED
Trial end date:
2024-09-27
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to compare general anesthesia with muscle relaxation and reversal of the relaxation at the end of surgery or without muscle relaxation in high-risk children having adenotonsillectomy surgery. The main questions it aims to answer are: 1. What is the impact of general anesthesia with muscle relaxation on opioid pain medication requirements during and after adenotonsillectomy? 2. What is the impact of general anesthesia with muscle relaxation on postoperative breathing complications and the adequacy of postoperative lung air volumes during breathing? Participants will wear three additional, noninvasive monitors during surgery, and one additional monitor after surgery. The amount of opioid pain medication required will be tracked, and the patient will be observed postoperatively for breathing complications. Measurements will be collected from the monitor worn postoperatively. Researchers will compare general anesthesia with muscle relaxation and reversal of relaxation at the end of surgery with general anesthesia without muscle relaxation to test the hypothesis that the approach using muscle relaxation reduces the amount of opioid pain medication required during and after surgery.
Phase:
PHASE4
Details
Lead Sponsor:
University of Texas Southwestern Medical Center
Collaborator:
Merck Sharp & Dohme LLC
Treatments:
Anesthesia
Neuromuscular Blockade
Neuromuscular Blocking Agents
Rocuronium
Sugammadex