Multiple Therapies in Treating Patients With Advanced Neuroblastoma
Status:
Completed
Trial end date:
2007-01-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation
may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells.
Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing
substances to them without harming normal cells. Radiation therapy uses high-energy x-rays to
damage tumor cells. Biological therapies use different ways to stimulate the immune system
and stop cancer cell from growing. Combining different types of therapies may kill more tumor
cells.
PURPOSE: Phase II trial to study the effectiveness of combining chemotherapy, monoclonal
antibody therapy, surgery, peripheral stem cell transplantation, radiation therapy, and
biological therapy in treating patients who have advanced neuroblastoma.