Multicentre Study on Rapid Versus Slow Withdrawal of Antiepileptic Monotherapy
Status:
Completed
Trial end date:
2021-11-01
Target enrollment:
Participant gender:
Summary
The main objective of the present study will be to establish whether a slow (within 160 days)
or a rapid (within 60 days) withdrawal schedule of antiepileptic monotherapy influence
relapse rate in adult patients with epilepsy, who have been seizure free for at least 2
years. Secondary objectives will be to establish the compliance rates with these two
schedules and the differences in terms of severity of relapses, based on the occurrence of
status epilepticus, seizure-related injuries and death.