Multicentral Preventive Antibiotics With Cystectomy Within Enhanced Recovery After Surgery
Status:
Recruiting
Trial end date:
2023-11-01
Target enrollment:
Participant gender:
Summary
The current usage of antibiotic prophylaxis (AP) in radical cystectomy (RC) is aimed to
reducing the incidence of surgical site infections and incidence of unnecessary prescribing
of antibiotics. There are a huge number of different AP protocols according to Urological
Associations. However, there is no convincing evidence to support variations and duration of
AP which requires a randomized clinical trial on AP when performing variants of RC with
uroderivation.
Research hypothesis: The use of prolonged antibiotic prophylaxis (5 days), depending on the
glomerular filtration rate, does not affect the incidence of postoperative complications.
Phase:
Phase 3
Details
Lead Sponsor:
N.N. Petrov National Medical Research Center of Oncology
Collaborator:
The Foundation for Cancer Research Support (RakFond)