Overview Multicenter Study of Hydroxyurea in Patients With Sickle Cell Anemia (MSH) Status: Completed Trial end date: 1994-06-01 Target enrollment: Participant gender: Summary To assess the efficacy and safety of orally administered hydroxyurea in the treatment of painful crises in patients with sickle cell anemia. Phase: Phase 3 Details Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)Treatments: Hydroxyurea