Multi-centre Study of HTL0018318 in Patients as an add-on to Standard-of-care

• Status: Completed
• Trial end date: 2018-07-16
• Target enrollment: 0
• Participant gender: All

Summary

Multi-centre study of HTL0018318 in patients with Alzheimer's disease as an add-on to standard-of-care

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Heptares Therapeutics Limited
• Collaborator: Allergan

Criteria

Inclusion Criteria:

1. Diagnostic evidence of Alzheimer's disease according to the 2011 National Institutes of Aging-Alzheimer's Association (NIA-AA) criteria

2. Participants with Alzheimer's disease on stable standard of care

Exclusion Criteria:

1. Presence of illness apart from Alzheimer's disease that could contribute to cognitive dysfunction

2. A current or history of clinically significant suicidal ideation within the past 6 months

3. Subjects who have been on anti-cholinergic and/or anti muscarinic treatment