Overview

Multi Cohort Study of Tazemetostat in Combination With Various Treatments For R/R Hematologic Malignancies

Status:
Recruiting
Trial end date:
2028-05-01
Target enrollment:
Participant gender:
Summary
This phase 1b/2 trial studies how safely the EZH2 inhibitor tazemetostat works with other therapies in various hematological malignancies. Tazemetostat has been found to be a safe and effective drug that works in patients with relapsed refractory follicular lymphoma. Giving tazemetostat in combination with other treatments may work better in treating patients with hematological malignancies and may improve disease response and durability of response.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Epizyme, Inc.
Treatments:
Acalabrutinib
Antibodies, Monoclonal
BB 1101
Daratumumab
Dexamethasone
Dexamethasone acetate
Lenalidomide
Pomalidomide