MsFLASH-01: Escitalopram for Menopausal Symptoms in Midlife Women
Status:
Completed
Trial end date:
2010-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test whether a medication reduces the number, severity and
bothersomeness of menopausal hot flashes. Escitalopram (also called Lexapro®) is a selective
serotonin reuptake inhibitor (SSRI). It is sold by prescription for depression and general
anxiety disorder. An SSRI increases serotonin, a brain substance that is believed to
influence mood. Serotonin may also affect brain levels of estradiol, a hormone related to hot
flashes. This research study will test whether escitalopram reduces menopausal hot flashes.
Phase:
N/A
Details
Lead Sponsor:
Fred Hutchinson Cancer Research Center
Collaborators:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Center for Complementary and Integrative Health (NCCIH) National Institute on Aging (NIA) Office of Research on Women's Health (ORWH)