Moxifloxacin in Situ Gel to Treat Periodontal Pocket.

• Status: Completed
• Trial end date: 2012-11-01
• Target enrollment: 0
• Participant gender: All

Summary

In this Randomized clinical trial locally delivered moxifloxacin in situ gel was evaluated as an adjunct to scaling and root planing for efficacy in the treatment of chronic periodontitis and for short-term effects on the periodontal microflora.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sri Hasanamba Dental College and Hospital
• Treatments: Fluoroquinolones; Moxifloxacin; Norgestimate, ethinyl estradiol drug combination

Criteria

Inclusion Criteria:

• patients with good systemic health

• Patients with Chronic periodontitis with sites with probing pocket depth (PPD) of ≥ 5 mm

• a minimum of 12 natural teeth with radiographic evidence of bone loss

• willingness to comply with the study protocol.

Exclusion Criteria:

• Patients with a history of drug allergy to quinolones or those who were taking medication that might interact with moxifloxacin

• Patients with history of antibiotic coverage in the 6 months preceding the study

• Pregnant or lactating patients.