Overview

Moxibustion in Osteoarthritis of the Knee

Status:
Completed
Trial end date:
2019-06-01
Target enrollment:
0
Participant gender:
All
Summary
This is a multicenter , double-blinded, double-dummy, randomized controlled clinical trial to evaluate the efficacy of moxibustion for osteoarthritis of the knee.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Chengdu University of Traditional Chinese Medicine
Treatments:
Diclofenac
Criteria
Inclusion Criteria:

- Male or female, aged between 40 and 75 years, with knee osteoarthritis diagnosed
according to American College of Rheumatology criteria

- Radiologic confirmation of osteoarthritis in 1 or both knees (Kellgren-Lawrence score
2 or 3)

- Had knee pain in one or both knee(s) of longer than 3 months'duration

- The average severity of knee pain at least 3 points on a10-point of visual analogue
scale(VAS)

- Never experienced moxibustion before this trial

- Participants who are willing to comply with our study protocol

- Participants who agree to sign the consent form

Exclusion Criteria:

- Subjects with serious diseases including cancer, uncontrolled hypertension, diabetes
mellitus requiring insulin injection, life-threatening cardiovascular or neurological
events, chronic respiratory disease, a haemorrhagic disorder and serious mental
diseases

- Subjects had pain in the knee may caused by inflammatory, malignant, autoimmune
disease or traumatic injury;

- Subjects received knee replacement surgery for the affected knee

- Subjects received knee arthroscopy within the past year, steroid or hyaluronic acid
injection in the knee joints within the previous 3 months

- Subject who currently participate in another clinical trial

- Subjects received physiotherapy or other treatments for osteoarthritis knee pain (with
the exception of non-steroidal anti-inflammatory drugs) during the previous 4 weeks;