Motor Recovery in Recent Stroke Patients Treated With Amphetamine and Physical Therapy
Status:
Completed
Trial end date:
2004-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine if giving amphetamines along with standard
rehabilitation speeds motor recovery after a stroke. In addition, if motor recovery is
improved, the study will also identify the areas of the brain involved with the recovery.
Researchers will use motor function ratings, PET scans, functional MRI (fMRI),
electroencephalographs, and transcranial magnetic stimulation (TMS) to evaluate patients.
Patients participating in the study will be placed in one of two groups;
1. Patients receiving dextroamphetamine and routine Rehabilitation Medicine
2. Patients receiving a placebo "sugar pill" and routine Rehabilitation Medicine
Patients that have improved motor recovery will undergo neuroimaging and neurophysiological
studies to identify areas of the brain involved.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)