Parkinson's disease (PD) is the second most common neurodegenerative disorder after
Alzheimer's disease (AD). Clinical manifestations of PD can vary, but a formal diagnosis
relies on the presence of bradykinesia with rigidity and/or rest tremor according to Movement
Disorder Society (MDS) criteria for PD. Non-motor symptoms, such as hyposmia, constipation,
depression, and rapid eye movement (REM) sleep behavior disorder, are common and can in many
cases manifest before classical motor symptoms. In later years, more emphasis has been put on
non-motor symptoms, especially in the early stages of PD and which is evident in the proposed
prodromal PD criterion by MDS.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Mostafa Bahaa
Treatments:
Carbidopa Carbidopa, levodopa drug combination Levodopa Montelukast