Monoamine Antagonist Therapies for Methamphetamine Abuse Prazosin
Status:
Completed
Trial end date:
2013-06-01
Target enrollment:
Participant gender:
Summary
This protocol will test the safety, effectiveness and the metabolism and action of prazosin
as a potential therapy for methamphetamine abuse. This will be accomplished by performing a
series of human laboratory studies. In each of these studies, the safety and effectiveness of
the test medication (prazosin) in the treatment of methamphetamine effects will be
determined. The study hypothesis is that prazosin will block the methamphetamine receptor
function, reducing the reinforcing effects of central nervous system effects in humans.