Monitoring and Treatment of Relapsed Leukemia Following Allogeneic Hematopoietic Stem Cell Transplantation in Children
Status:
Terminated
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
This study aims to monitor patients for relapse of the leukemia following allogeneic
Hematopoietic Stem Cell Transplantation (HSCT) in order to identify patients early in
relapse, with a low burden of disease, when interventions may be more successful by
monitoring of peripheral blood lineage specific chimerism. Once disease has been confirmed,
patients will initiate a novel combination of bortezomib and pravastatin.
Phase:
Phase 1
Details
Lead Sponsor:
Reuven Schore
Collaborators:
Hyundai Hope On Wheels Millennium Pharmaceuticals, Inc.