Molecular Diversity of HIV-1 Group O Strains and Treatment Management in Cameroon
Status:
Completed
Trial end date:
2016-09-01
Target enrollment:
Participant gender:
Summary
Infections with HIV-1 group O are found in 1 to 3 % of persons living with HIV in Cameroon.
The natural history and treatment response is not well understood. The natural resistance to
non nucleoside reverse transcriptase inhibitors and their possible low sensitivity to
protease inhibitors complicate the choice of an adequate treatment options.
This observational study is aimed at evaluating the antiretroviral treatment response of
HIV-1 group O infected patients in comparison with HIV-1 group M infected patients. The
proposed standardized follow-up will facilitate a better understanding of the natural history
and treatment specificities to improve the patients management.
This is a non randomized study, open label, with standardized follow-up. A total of 171
patients
Details
Lead Sponsor:
ANRS, Emerging Infectious Diseases French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)