Modulation of Reinforcement Learning

• Status: Completed
• Trial end date: 2016-08-07
• Target enrollment: 0
• Participant gender: Male

Summary

This study aims to examine the modulation of neuronal and behavioural parameters of social reinforcement learning.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: RWTH Aachen University
• Treatments: Oxytocin

Criteria

Inclusion Criteria:

• Age between 18 and 26 years

• male

• IQ>80

• written informed consent

• proband understands character, extent and individual consequences of the study

• competent persons who are able to follow the instructions of the study personnel

• for ASD patients: assured ASD diagnosis, comply of the ASD criteria ADI-R/ADOS-G

Exclusion Criteria:

• prosopagnosia

• anaphylaxis of oxytocin or other chemical substances

• metal inside the body or other contraindications of mri scan

• physical illness which can affect the examinations or endanger the proband

• actual or assumed drug or alcohol abuse

• persons who are accommodated in an institution because of court or administrative order

• persons with a relationship of dependence to the sponsor or investigator

• healthy probands: psychiatric disorder according to ICD-10-WHO F at the moment and in history, continuous drug-intake at time of measurements

• patients with ASD: psychiatric disorder according to ICD-10-WHO F (except ASD disorder in patient group) during the last 12 month being not treated, continuous drug-intake at time of measurements (psychotropic medication), exception: stimulants used for treatment of attention disorders, if they can come off for the measurements