Overview

Modufolin (Arfolitixorin) in Combination With 5-Fluorouracil Alone or Together With Oxaliplatin or Irinotecan in Colorectal Cancer

Status:
Completed

Trial end date:
2020-01-30

Target enrollment:

Participant gender:

Summary

The purpose is to characterise the tolerability of Modufolin (arfolitixorin) in combination with 5-FU alone, in combination with 5-FU and Oxaliplatin, in combination with 5-FU and Irinotecan and in combination with 5-FU, Oxaliplatin and Bevacizumab. Another purpose is to investigate 4 doses of Modufolin to identify the best dose for further assessment.

Phase:

Phase 1/Phase 2

Details

Lead Sponsor:

Isofol Medical AB

Treatments:

Bevacizumab
Camptothecin
Fluorouracil
Irinotecan
Oxaliplatin
Tetrahydrofolates