Overview

Modified Dosage for Moderate Acute Malnutrition (MODAM-MAM)

Status:
Not yet recruiting
Trial end date:
2026-09-25
Target enrollment:
Participant gender:
Summary
Protocols for the community-based management of acute malnutrition (CMAM) have not changed significantly for more than 20 years, with relatively complex treatment protocols and persistent supply chain challenges that have limited overall program coverage, leaving millions of malnourished children without care annually. The overarching goal of this research project is to simultaneously test two novel simplified approaches in CMAM with potential to improve program coverage. The simplified approach includes two parallel clinical trials for SAM and MAM treatment. Two fixed-dose regimes of RUTF will be tested against the current fixed-dose regimen of RUTS for children with MAM.
Phase:
N/A
Details
Lead Sponsor:
Action Against Hunger USA
Collaborators:
Ethiopian Public Health Institute
University of Washington
Treatments:
Amoxicillin