Modified BPaL Regimen for Managing Pre-XDR TB and MDR (TI/NR) TB in India
Status:
Recruiting
Trial end date:
2024-03-31
Target enrollment:
Participant gender:
Summary
Existing problem with DR TB management:
Injectable regimens for longer duration with toxicity Poor adherence, treatment failures,
continued transmission
Need of the study:
Oral regimens of shorter duration Improved treatment adherence Implementation of
community-based models of care Reduction in direct costs and indirect costs of patients
Improved treatment outcomes
Need for shorter, tolerable and effective regimen
Hence modified BPaL regimen is designed to study the newer shorter oral in varying doses of
Linezolid for pre XDR Tb patients and MDR TI/NR patients
Phase:
Phase 3
Details
Lead Sponsor:
Tuberculosis Research Centre, India
Collaborators:
BJ Medical College, Ahmedabad Govt. Medical College, Surat International Union Against Tuberculosis and Lung Diseases KGMU, Lucknow NITRD, New Delhi RBIPMT, Delhi Sarvodaya Charitable Trust Hospital, Ghatkopar, Mumbai Shatabdi Centenary Hospital, Govandi, Mumbai SN Medical College, Agra