Modelle 001, TS-inhibition in Colorectal Liver Metastases Comparing Arfolitixorin and Calciumfolinate
Status:
Recruiting
Trial end date:
2021-11-01
Target enrollment:
Participant gender:
Summary
A study that is blinded to the patient and the investigator where the combination of
Arfolitixorin + 5-FU is compared to Calciumfolinate + 5-FU. The patients will be randomised
and will receive the above described combination as IV bolus injections, peroperatively in
conjuction with collection of the first tissue sample.
A low dose (30 mg) and a high dose (120) mg of Arfolitixorin will be used in order to
investigate the relation between dose of Arfolitixorin and TS-inhibition.