Modafinil for Freezing of Gait (FOG) in Parkinson's Disease (PD)
Status:
Completed
Trial end date:
2019-11-12
Target enrollment:
Participant gender:
Summary
Freezing of gait is a late stage complication of Parkinson's disease in which patients note
that their feet feel stuck or glued to the ground. This can lead to imbalance and falls and
the secondary complications that can result from falls such as fractures and
hospitalizations. While levodopa can help freezing of gait in some patients, it does not help
in all, and the dose needed to treat freezing may be limited by side effects of the
medications. Currently there are no treatments targeted towards freezing of gait and the goal
of this research is to see if Modafinil could be one such drug to help freezing of gait in
Parkinson's disease.