Overview

Modafinil and Cognitive Function in POTS

Status:
Active, not recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
A common complaint among patients with Postural Tachycardia Syndrome (POTS) is "brain fog" or difficulty concentrating. This problem is poorly understood. The purpose of this study is to better understand the cognitive dysfunction associated POTS, and to determine optimal treatment strategies for this condition. In this study, the investigators will test the hypothesis that acute administration of the psychostimulant drug modafinil can improve seated measures of cognitive function in patients with POTS.
Phase:
Early Phase 1
Details
Lead Sponsor:
Vanderbilt University
Vanderbilt University Medical Center
Treatments:
Armodafinil
Modafinil
Propranolol