Mitomicin C for Prevention Postoperative Endoscopic Sinus Surgery Synechia and QOL in Chronic Rhinosinusitis
Status:
Completed
Trial end date:
2017-12-01
Target enrollment:
Participant gender:
Summary
Primary objective
- To compare the incidence of postoperative nasal synerchia between Mitomicin C and
placebo in patients at 6 months after endoscopic sinus surgery
- To validate the Thai version of disease-specific quality of life tool SNOT-22
Secondary objectives
- To compare the clinical signs and symptoms of CRS in patients who receive Mitomicin C
with those who receive placebo
- To compare the disease-specific quality of life in patients who receive Mitomicin C with
those who receive placebo
- To compare the side effects of Mitomicin C versus placebo