Misoprostol for the Treatment of Incomplete Abortion
Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
This randomized study will examine the efficacy, safety and acceptability of misoprostol for
treatment of incomplete abortion.
Women diagnosed with incomplete abortion will be randomized to receive one of the following
regimens:
In Tanzania and Mozambique:
1. 600 mcg of oral misoprostol in one dose, or
2. Standard surgical treatment (MVA)
In Moldova and Madagascar:
1. 600 mcg of oral misoprostol in one dose, or
2. 400 mcg of sublingual misoprostol in one dose.
In Burkina Faso and Vietnam:
1. 400 mcg of sublingual misoprostol in one dose.
We hypothesize that treatment of incomplete abortion with either 400 mcg sublingual
misoprostol, 600 mcg oral misoprostol or MVA are equally effective in evacuating the uterus.
Phase:
N/A
Details
Lead Sponsor:
Gynuity Health Projects
Collaborators:
Befelatanana Maternity Centre Cuchi General District hospital Hôpital de District Sanitaire Dandé Hôpital de District Sanitaire de Ziniaré Jose Macamo Hospital Kagera Regional Hospital Municipal Clinical Hospital No. 1 National OBGYN hospital Tudu hospital